Chemotherapy Biotherapy Certification ONS Practice Testq

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Prepare for the ONS Chemotherapy Biotherapy Certification Exam. Leverage flashcards and multiple choice questions, complete with hints and explanations. Equip yourself for exam success!

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Which of the following best characterizes the mechanism of action of hypoxic cell sensitizers?

Increase enzyme activity
Alter DNA structure
Enhance cellular oxygenation
Inhibit protein synthesis

The correct answer is: Enhance cellular oxygenation

Hypoxic cell sensitizers function primarily by enhancing cellular oxygenation. Tumors often contain regions of hypoxia due to inadequate blood supply, which makes them resistant to certain treatments like radiation therapy. The presence of oxygen is crucial in the radiation treatment of tumors; it enhances the efficacy of radiation by creating free radicals that damage cellular components, particularly DNA. By increasing the oxygen levels in hypoxic tumor cells, these sensitizers improve the effectiveness of radiation therapy, allowing for better tumor control and potentially leading to improved patient outcomes. Understanding the role of oxygen in enhancing radiosensitivity is vital for healthcare professionals focusing on cancer treatment strategies.