Chemotherapy Biotherapy Certification ONS Practice Testq

Which of the following administration routes allows direct delivery of chemotherapy to the bladder?

1. Intrathecal

2. Intraperitoneal

3. Oral

4. Intracavity

The correct answer is: Intracavity

The direct delivery of chemotherapy to the bladder is effectively achieved through the intracavity route. This method involves instilling the chemotherapy agent directly into the bladder, enabling high local concentrations of the drug at the site of the tumor while minimizing systemic exposure and potential side effects. Intracavity administration is particularly beneficial for treating bladder cancers, as it allows for direct action on the cancerous tissue and can enhance the therapeutic effect. By targeting the bladder directly, this approach improves the efficacy of the chemotherapy while reducing the risk of systemic toxicity often seen with other routes of administration. In the context of the other listed routes, intrathecal administration delivers drugs directly into the cerebrospinal fluid and targets the central nervous system, making it unsuitable for bladder treatment. Intraperitoneal administration involves delivering medications into the abdominal cavity and is typically used for abdominal cancers or malignancies with peritoneal dissemination. Oral administration involves swallowing medications, which travel through the digestive system and are absorbed into the bloodstream, thus not providing localized treatment to the bladder.