Chemotherapy Biotherapy Certification ONS Practice Testq

Which cells in the body are least likely to be affected by chemotherapy?

1. Normal gut lining cells

2. Hair follicle cells

3. Cells of the immune system

4. Cells in a dormant state

The correct answer is: Cells in a dormant state

Chemotherapy targets rapidly dividing cells, as these treatments are designed to disrupt the cell cycle and inhibit the growth of cancerous cells. Cells in a dormant state, or quiescent cells, are less likely to be affected by chemotherapy because they are not actively undergoing division. Since these dormant cells do not progress through the cell cycle, they are not as susceptible to agents that specifically target dividing cells. In contrast, normal gut lining cells, hair follicle cells, and cells of the immune system are all examples of rapidly dividing cells. These cell types are actively engaged in division and can be adversely affected by chemotherapy, leading to common side effects such as nausea, hair loss, and immunosuppression. Thus, the correct answer highlights the resilience of dormant cells against the cytotoxic effects of chemotherapy compared to those actively undergoing cell division.